Alpha and Beta-Hexachlorocyclohexanes: Environmental Health Criteria 123

This document provides an evaluation of two isomers of hexachlorocyclohexane, which are by-products in the manufacturing of the insecticide lindane. Since these isomers lack insecticidal properties, their presence in the environment is a significant concern. The report details their chemical and physical properties, analytical methods, and sources of environmental and human exposure. It extensively covers their transport, distribution, and transformation in various media, including their bioconcentration in microorganisms, invertebrates, and fish. The document also assesses the effects on organisms in the environment and experimental animals, examining kinetics, metabolism, toxicity, carcinogenicity, and effects on humans. Ultimately, it offers conclusions and recommendations for the protection of human health and the environment, highlighting the risks associated with these compounds and suggesting measures to mitigate environmental pollution.