Determination of Mercury and Creatinine in Urine

This analytical guidance document, developed by Euro Chlor as part of its Responsible Care programme to promote continuous improvement in health, safety, and environmental standards associated with chlorine manufacture, describes standardised procedures for biological monitoring of mercury exposure in the chlor-alkali industry. It outlines urine sampling, preservation, and storage requirements, and details analytical methods for determining total mercury and creatinine concentrations in urine. The document specifies analytical principles, equipment, reagents, calibration procedures, quality control measures, and calculation methods for expressing mercury exposure relative to creatinine levels. It also provides guidance on detection limits, blank value control, and analytical precision