Experimental Aflatoxic Cancerogenesis and Undernutrition Ultrastructural and Pathomorphological Basis

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dc.contributor.authorUnited Nations Environment Programme
dc.contributor.authorUSSR State Committee for Science and Technology
dc.contributor.authorFood and Agriculture Organization of the United Nations
dc.contributor.organizationScience Division
dc.date.accessioned2019-08-23T07:02:16Z
dc.date.available2019-08-23T07:02:16Z
dc.date.issued1985
dc.descriptionThis document is a study on the experimental effects of aflatoxin carcinogenesis and undernutrition, focusing on ultrastructural and pathomorphological changes in liver cells. It explores the toxic and carcinogenic impacts of aflatoxins, particularly aflatoxin B1, on various animal models, including rats, monkeys, and ducks, with detailed observations on liver necrosis, dysplasia, and tumor development. The study highlights the interplay between aflatoxin exposure and nutritional deficiencies, such as low protein diets, and their synergistic role in exacerbating liver damage and cancer risk. Electron microscopy reveals critical cellular changes, including nucleolar segregation, endoplasmic reticulum disruption, and lysosomal activity. The document also discusses epidemiological correlations between aflatoxin-contaminated food and liver cancer incidence in regions like Africa and Asia.en
dc.formatText
dc.identifier.urihttps://wedocs.unep.org/handle/20.500.11822/29615
dc.languageEnglish
dc.page.number29 p.
dc.rights.accessLevelPublic
dc.subjecthazardous waste
dc.subjectchemical
dc.subjectcancer
dc.subjectRussia
dc.subject.sdgSDG 3 - Good Health and Well-Being
dc.titleExperimental Aflatoxic Cancerogenesis and Undernutrition Ultrastructural and Pathomorphological Basisen
dc.typeCommunication or other resource

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