Cadmium Exposure and Indicators of Kidney Function - MARC Report Number 29

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dc.contributor.authorUnited Nations Environment Programme
dc.contributor.authorRockefeller Foundation
dc.contributor.authorMonitoring and Assessment Research Centre
dc.contributor.organizationEconomy Division
dc.contributor.otherHutton, Malcolm
dc.date.accessioned2019-04-19T15:41:40Z
dc.date.available2019-04-19T15:41:40Z
dc.date.issued1983
dc.descriptionThis technical assessment presents the relationship between cadmium exposure and early indicators of kidney dysfunction in humans. Conducted by the Monitoring and Assessment Research Centre (MARC) with support from UNEP and the European Commission, the report synthesizes data from epidemiological studies of populations in Japan and a group of occupationally exposed workers. It examines methods for estimating cadmium exposure—such as dietary intake, faecal excretion, and urinary cadmium levels—and evaluates their reliability. The study emphasizes the use of urinary β2-microglobulin as the principal biomarker for renal effects and critically assesses its specificity, stability, and diagnostic relevance. Dose-response and dose-effect analyses are conducted using regression and probit analysis, showing that while most of the population is protected by WHO's provisional tolerable cadmium intake, a small percentage may still show early renal effects.en
dc.formatpdf
dc.identifier.isbn0 905918 20 6
dc.identifier.urihttps://wedocs.unep.org/handle/20.500.11822/28019
dc.languageEnglish
dc.page.number57 p.
dc.rights.accessLevelPublic
dc.subjectcadmium
dc.subjectchemical
dc.subjecthealth
dc.subject.sdgSDG 3 - Good Health and Well-Being
dc.titleCadmium Exposure and Indicators of Kidney Function - MARC Report Number 29en
dc.typeTechnical report

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