RT Report T1 Environmental Health Criteria 98 - Tetramethrin A1 World Health Organization, K1 environmental health K1 chemical K1 aquatic ecology K1 terrestrial ecosystem SN 92 4 154298 5 YR 1990 FD 1990 LK https://wedocs.unep.org/handle/20.500.11822/29410 UL https://wedocs.unep.org/handle/20.500.11822/29410 NO Tetramethrin was first synthesized in 1964 and first marketed in 1965. Chemically, it is an ester of chrysan-themic acid (2,2-imethyl-3-(2,2-dimethylvinyl)-cyclopro-panecarboxylic acid) with 3,4,5,6 tetrahydrophthalimido-methyl alcohol. It is a mixture of four stereoisomers:[1R,trans], [1R,cis], [1S,trans], and [1S,cis]. In techni-cal products, the composition ratio of the isomers is roughly 4:1:4:1. Among the isomers, the [1R,trans] isomer is the most active biologically followed by the [1R,cis] isomer. A mixture of the [1R,cis] and [1R,trans] isomers (1:4) is commercialized under the trade name of `Neo-Pynamin Forte' (designated as 1R, cis/trans-tetramethrin in this monograph). DS UN Environment Document Repository RD Sep 19, 2026