RT Report T1 Acetonitrile: Environmental Health Criteria 154 A1 World Health Organization, K1 chemical K1 environmental health K1 toxic substance SN 92 4 157154 3 YR 1993 FD 1993 LK https://wedocs.unep.org/handle/20.500.11822/29461 UL https://wedocs.unep.org/handle/20.500.11822/29461 NO Acetonitrile (CH3CN) is a by-product of acrylonitrile manufacture. It may also be formed by the combustion of wood and vegetation. It is a liquid with an ether-like odour. Acetonitrile is a volatile, highly polar solvent used to extract fatty acids and animal and vegetable oils. It is used in the petrochemical industry in extractive distillation based on its selective miscibility with organic compounds. It is used as a solvent for spinning synthetic fibres and in casting and moulding plastics. In laboratories, it is widely used in high-performance liquid chromatographic (HPLC) analysis and as a solvent for DNA synthesis and peptide sequencing. DS UN Environment Document Repository RD Sep 17, 2026