RT Report
T1 Guidelines for the Study of Genetic Effects in Human Populations: Environmental Health Criteria 46
A1 United Nations Environment Programme, 
A1 World Health Organization, 
A1 International Labour Organisation, 
K1 genetic
K1 population
K1 epidemiology
K1 mutation
K1 chromosome
K1 death
K1 health
SN 92 4 150186 5
YR 1985
FD 1985
LK https://wedocs.unep.org/handle/20.500.11822/29524
UL https://wedocs.unep.org/handle/20.500.11822/29524
NO The extent to which human somatic and germinal mutation frequencies may be increased by exposure to ionizing radiation and to the variety of chemicals that characterize modern societies has been a matter of concern in recent years. Somatic mutations, either genic or chromosomal, are not transmitted to the offspring of an exposed individual. However, increases in the frequency of these mutations may contribute to an increase in the frequency of acquired disorders, for example, cancer. Increases in the frequency of germinal mutations, genic or chromosomal, are likely to contribute to inherited defects in the offspring of individuals exposed to mutagenic agents. There is, therefore, a clear need to develop and apply methods to study exposed populations at risk of increased levels of Somatic or germinal mutations.
DS UN Environment Document Repository
RD Sep 23, 2026