RT Report T1 The Ozone Depletion Problem (An Example of Harm Commitment): MARC Report Number 1 A1 United Nations Environment Programme, A1 Rockefeller Foundation, A1 International Council of Scientific Unions, A2 Machta, Lester K1 ozone-depleting substance K1 climate K1 radiation effect K1 ultraviolet radiation K1 environmental impact assessment K1 cancer K1 chlorofluorocarbon SN 0 905918 002 YR 1976 FD 1976 LK https://wedocs.unep.org/handle/20.500.11822/27969 UL https://wedocs.unep.org/handle/20.500.11822/27969 NO This report provides a clear, accessible evaluation of the complex challenge posed by ozone layer depletion and its long-term consequences for human health and the environment. It details the scientific understanding of how specific chemicals, including chlorofluorocarbons (CFCs) and oxides of nitrogen, are released through human activities and transported to the stratosphere, where they catalytically destroy ozone. The report uses the dose and harm commitment concept to show that the environmental release of these chemicals leads to a committed increase in ground-level ultraviolet radiation, which is strongly associated with higher rates of skin cancer, particularly among susceptible populations. It discusses the significant scientific uncertainties that persist in modeling these impacts, accentuating the need for continued atmospheric monitoring and laboratory research. An annex offers a thorough economic analysis of restricting CFC emissions, balancing the technological and cost implications against the environmental and public health benefits, and concludes with actionable recommendations for policy, monitoring, and ongoing assessment. DS UN Environment Document Repository RD Sep 19, 2026