RT Report
T1 Principles and Methods for the Assessment of Nephrotoxicity Associated with Exposure to Chemicals - Environmental Health Criteria 119
A1 World Health Organization, 
K1 toxic substance
K1 disease
K1 chemical
SN 92 4 157119 5
YR 1991
FD 1991
LK https://wedocs.unep.org/handle/20.500.11822/29539
UL https://wedocs.unep.org/handle/20.500.11822/29539
NO Nephrotoxicity can be defined as renal disease or dysfunction that arises as a direct or indirect result of exposure to medicines, and industrial or environmental chemicals. It is well established that toxic nephropathies are not restricted to a single type of renal injury. Some chemicals target one discrete anatomical region of the kidney and may affect only one cell type. Chemical insult to the kidney may result in a spectrum of nephropathies that are indistinguishable from those that do not have a chemical etiology.
DS UN Environment Document Repository
RD Sep 18, 2026